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AGC’s AMOLEA™ 1224yd is an ASHRAE A1 certified, non-flammable fourth-generation refrigerant with no impact on ozone depletion and a GWP value under 1 for use as an alternative to HFCs. Its physical properties are similar to those of HFC-245fa, while achieving 99.9% less GWP and lower toxicity (LC50>213,100 ppm, AEL 1000 ppm). Furthermore, it has good chemical/thermal stability and compatibility with most commonly used metals, plastics, and elastomers. It is ideal for use in centrifugal chillers, Organic Rankine Cycle (ORC, binary cycle) and waste heat recovery heat pumps.


  • Little impact on the natural environment
  • Good compatibility with most commonly used oils, metals, plastics and elastomers
  • Better chemical and thermal stability than HCFC-123, HFOs and HCFOs
  • Excellent energy savings
  • Low toxicity
  • Easy to retrofit to equipment used for HFC-245fa and HCFO-1233zd(E)

  • Centrifugal Chillers
  • Rankine Cycle System
  • Waste Heat Recovery Pumps
A next-generation, low-GWP replacement for HFC.
AGC’s AMOLEA™ - fourth-generation refrigerant.
AGC Chemicals